BRAVE B-Curious
Monitor nanoparticle behavior in real-time
If common methods of particle analysis aren’t up to the challenge and you want a deeper understanding of particle behavior, you are now just one click away from revolutionizing your measurement.
Do you want to make groundbreaking discoveries and gain deep insights into your samples? With BRAVE B-Curious you have the perfect tool for these discoveries. You will get nanoparticle characterization results like never before. Prepare to be surprised: conventional methods of particle analysis like DLS, NTA or Laser Diffraction only show a fraction of what the revolutionary technology of BRAVE B-Curious can measure. The patented OF2i method gives you detailed insights into all the particle populations of your sample and tracks changes in nanoparticle size distributions and particle concentrations in real-time and continuously. You will get a better understanding of particle behavior and learn more about the processes. All measurement results are representative and statistically relevant. As a true pioneer you can raise your research to a new level with BRAVE B-Curious.
Everyone who has worked with the conventional methods for nanoparticle characterization in the lab already is familiar with the feeling of discontent – or even frustration – resulting from the limits of measurability. Dynamic Light Scattering, Nanoparticle tracking Analysis and Laser Diffraction only allow limited insights into the actual particle behavior and typically struggle to measure ultra-low particle concentrations. Get ready for BRAVE B-Curious, which lets you analyze particle behavior continuously and in real-time over minutes and hours. The results have single-particle sensitivity based on measurement of up to 2500 particles per minute. This makes them statistically relevant and representative of the whole particle population. With this time-resolved approach you can monitor kinetic processes like aggregation, condensate formation, agglomeration, dissolution or dissociation and analyze them in real-time and in one continuous measurement.
With BRAVE B-Curious you can:
A number of methods for particle characterization are available. These all have their advantages and disadvantages and are suited for different areas of application. BRAVE B-Curious with the patented OF2i-method has a number of advantages over conventional approaches.
If you are used to measuring your samples with Nanoparticle Tracking Analysis, OF2i brings you the following benefits:
If you are used to analyzing particles with Dynamic Light Scattering, you can look forward to next-level results and benefits such as:
Laser diffraction is one of the most commonly used methods for particle characterization in the laboratory, mainly because it is so versatile. However, laser diffraction does have some drawbarcks. Using the OF2i principle brings the following benefits compared to laser diffraction.
Electron microscopes deliver impressive high-resolution images. Despite offering in-depth analysis, BRAVE B-Curious still has benefits compared to this method of particle analysis.
BRAVE B-Curious helps you overcome many of the limitations of conventional methods. For the first time ever, you can monitor particles in real-time and continuously over a time period you define. You get unprecedented insights into your processes and the behavior of particle populations – an open door to groundbreaking discoveries.
Particle size distribution (actual D-values)
Sample kinetics such as dissolution, dissociation, condensate formation, crystallization and protein-protein interactions
Anomalies, aggregates, large-particle tails and other oversized particles
Particle concentrations (even down to a few particles per milliliter)
Particle size with single-particle sensitivity
You want to see particles like never before?
Get to know BRAVE B-Curious. We'd love to answer all your questions.
We built BRAVE B-Curious as a modular platform, so you can configure it to perfectly suit your needs. Our experts will work together with you on a custom-tailored setup. Your BRAVE B-Curious will be aligned with your needs and ideal for your research – with the possibility of future upgrades and additional modules at a later date.
Module for concentration determination
Allows the detection of ultra-low concentrations (e.g. nanoplastics or water for injections) at particle concentrations down to a few particles per milliliter.
Module for time-resolved sizing
Allows the monitoring of PSD continuously and directly out of containers. This way you can monitor sample behavior such as agglomeration, formation, dissolution, aggregation, dissociation, self-assembly and more. Detection range: 50 nm* to 5 µm (*sample-dependent)
Module for size range extension
Allows the detection of large-particle tails, LPC, aggregation behaviors and anomalies. Detection range: 50 nm* to 50 µm (*sample-dependent)
Module for particle analytics
(coming soon)
Allows the identification and characterization of particle populations via Raman spectroscopy.
Module for low-volume sizing
Allows the determination of PSD from low volumes, starting at 20 µl (sample-dependent)
Module for Raman tweezers
(coming soon)
Allows the trapping of particle populations for characterization with Raman spectroscopy.
BRAVE B-Curious is the ideal instrument for groundbreaking research in the field of nanoparticle characterization and offers a new approach. You obtain unprecedented insights into particle behavior, sample processes and a complete overview of the particle populations.
BRAVE B-Curious implements a new approach to particle analysis: OF2i. This new principle of particle characterization uses opto-fluidic forces to accelerate, decelerate, trap or even redirect nanoparticles. OF2i (OptoFluidic Force Induction) allows you to measure particle size, particle size distributions and particle concentrations more exactly than ever before – with single-particle sensitivity and statistical relevance. Unlike established methods, the patented OF2i method is not dependent on Brownian motion. With OF2i you measure continuously and in real-time and can even resolve complex, polydisperse systems.
H.A.N.S. supports you with:
In its development phase, BRAVE B-Curious was already in use by some selected partners at universities and research institutes. As of March 2023 you can order your own BRAVE B-Curious. Contact us or book a live demonstration and we will answer all your questions. What are you waiting for? It’s time to make groundbreaking discoveries!
You are just one click away from revolutionizing your research!
PARTICLE MEASUREMENT
As a partner in the MOZART project (MOZART for safe & sustainable by-design metallic coatings & engineered surfaces (RIA)), we received funding from the European Commission as part of the EU Horizon 2020 program.